Mechanism of How Salt-Gradient-Induced Charges Affect the Translocation of DNA Molecules through a Nanopore

Experiments using nanopores demonstrated that a salt gradient enhances the capture rate of DNA and reduces its translocation speed. These two effects can help to enable electrical DNA sequencing with nanopores. Here, we provide a quantitative theoretical evaluation that shows the positive net charge...

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Detalhes bibliográficos
Main Authors: He, Yuhui, Tsutsui, Makusu, Scheicher, Ralph H., Fan, Chun, Taniguchi, Masateru, Kawai, Tomoji
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736693/
https://ncbi.nlm.nih.gov/pubmed/23931325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.05.065
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