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Proteomic Investigation of the Sinulariolide-Treated Melanoma Cells A375: Effects on the Cell Apoptosis through Mitochondrial-Related Pathway and Activation of Caspase Cascade

Sinulariolide is an active compound isolated from the cultured soft coral Sinularia flexibilis. In this study, we investigated the effects of sinulariolide on A375 melanoma cell growth and protein expression. Sinulariolide suppressed the proliferation and migration of melanoma cells in a concentrati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Hsing-Hui, Su, Jui-Hsin, Chiu, Chien-Chih, Lin, Jen-Jie, Yang, Zih-Yan, Hwang, Wen-Ing, Chen, Yu-Kuei, Lo, Yu-Hsuan, Wu, Yu-Jen
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736442/
https://ncbi.nlm.nih.gov/pubmed/23880933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md11072625
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