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Molecular Pathways: Inhibiting steroid biosynthesis in prostate cancer

A significant proportion of castration-resistant prostate cancers (CRPC) remain driven by ligand activation of the androgen receptor. Although the testes are the primary source of testosterone, testosterone can also be produced from peripheral conversion of adrenal sex hormone precursors dehydroepia...

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Detalhes bibliográficos
Main Authors: Ferraldeschi, Roberta, Sharifi, Nima, Auchus, Richard J., Attard, Gerhardt
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736095/
https://ncbi.nlm.nih.gov/pubmed/23470964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0931
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