Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis

We previously suggested that, in obese animals and humans, white adipose tissue inflammation results from the death of hypertrophic adipocytes; these are then cleared by macrophages, giving rise to distinctive structures we denominated crown-like structures. Here we present evidence that subcutaneou...

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Autors principals: Giordano, Antonio, Murano, Incoronata, Mondini, Eleonora, Perugini, Jessica, Smorlesi, Arianna, Severi, Ilenia, Barazzoni, Rocco, Scherer, Philipp E., Cinti, Saverio
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735940/
https://ncbi.nlm.nih.gov/pubmed/23836106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M038638
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