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Mechanisms, function and clinical applications of DNp73

p73, has two distinct promoters, which allow the formation of two protein isoforms: full-length transactivating (TA) p73 and an N-terminally truncated p73 species (referred to as DNp73) that lacks the N-terminal transactivating domain. Although the exact cellular function of DNp73 is unclear, the hi...

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Hlavní autoři: Di, Cuixia, Yang, Lina, Zhang, Hong, Ma, Xiaofei, Zhang, Xin, Sun, Chao, Li, Hongyan, Xu, Shuai, An, Lizhe, Li, Xun, Bai, Zhongtian
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735700/
https://ncbi.nlm.nih.gov/pubmed/23708520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24967
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