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Primary vascularization of allografts governs their immunogenicity and susceptibility to tolerogenesis

We investigated the influence of allograft primary vascularization on alloimmunity, rejection and tolerance in mice. First, we showed that fully allogeneic primarily vascularized and conventional skin transplants were rejected at the same pace. Remarkably, however, short-term treatment of mice with...

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Autori principali: Kant, Cavit D., Akiyama, Yoshinobu, Tanaka, Katsunori, Shea, Susan, Connolly, Sarah E, Germana, Sharon, Winn, Henry J., LeGuern, Christian, Tocco, Georges, Benichou, Gilles
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735678/
https://ncbi.nlm.nih.gov/pubmed/23833234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202092
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