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Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis
Systemic inhibition of Notch signaling was previously shown to attenuate experimental autoimmune encephalomyelitis (EAE), a disease model of multiple sclerosis in mice. Different studies attributed these effects to decreased T-bet and IFNγ expression, enhanced regulatory T cell function, reduced T c...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735619/ https://ncbi.nlm.nih.gov/pubmed/23825310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301116 |
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