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Expression of Drug Targets in Patients Treated with Sorafenib, Carboplatin and Paclitaxel

INTRODUCTION: Sorafenib, a multitarget kinase inhibitor, targets members of the mitogen-activated protein kinase (MAPK) pathway and VEGFR kinases. Here we assessed the association between expression of sorafenib targets and biomarkers of taxane sensitivity and response to therapy in pre-treatment tu...

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Détails bibliographiques
Auteurs principaux: Jilaveanu, Lucia B., Zhao, Fengmin, Zito, Christopher R., Kirkwood, John M., Nathanson, Katherine L., D'Andrea, Kurt, Wilson, Melissa, Rimm, David L., Flaherty, Keith T., Lee, Sandra J., Kluger, Harriet M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735539/
https://ncbi.nlm.nih.gov/pubmed/23936348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069748
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