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Phase III Trial of Carboplatin and Paclitaxel With or Without Sorafenib in Metastatic Melanoma

PURPOSE: The primary objective of this study was to determine whether carboplatin, paclitaxel, and sorafenib (CPS) improve overall survival (OS) compared with carboplatin and paclitaxel (CP) in chemotherapy-naive patients with metastatic melanoma. PATIENTS AND METHODS: In this double-blind, randomiz...

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Pubblicato in:J Clin Oncol
Autori principali: Flaherty, Keith T., Lee, Sandra J., Zhao, Fengmin, Schuchter, Lynn M., Flaherty, Lawrence, Kefford, Richard, Atkins, Michael B., Leming, Philip, Kirkwood, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878104/
https://ncbi.nlm.nih.gov/pubmed/23248256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.42.1529
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