Tyrosine Kinase BMX Phosphorylates Phosphotyrosine-Primed Motif Mediating the Activation of Multiple Receptor Tyrosine Kinases

The nonreceptor tyrosine kinase BMX (bone marrow tyrosine kinase gene on chromosome X) is abundant in various cell types and activated downstream of phosphatidylinositol-3 kinase (PI3K) and the kinase Src, but its substrates are unknown. Positional scanning peptide library screening revealed a marke...

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Auteurs principaux: Chen, Sen, Jiang, Xinnong, Gewinner, Christina A., Asara, John M., Simon, Nicholas I., Cai, Changmeng, Cantley, Lewis C., Balk, Steven P.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735445/
https://ncbi.nlm.nih.gov/pubmed/23716717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003936
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