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Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling

BACKGROUND: Although there is extensive evidence for the amoeboid invasiveness of cancer cells in vitro, much less is known about the role of amoeboid invasiveness in metastasis and the importance of Rho/ROCK/MLC signaling in this process. RESULTS: We analyzed the dependence of amoeboid invasiveness...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kosla, Jan, Paňková, Daniela, Plachý, Jiří, Tolde, Ondřej, Bicanová, Kristýna, Dvořák, Michal, Rösel, Daniel, Brábek, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735423/
https://ncbi.nlm.nih.gov/pubmed/23899007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-51
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