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Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling

BACKGROUND: Although there is extensive evidence for the amoeboid invasiveness of cancer cells in vitro, much less is known about the role of amoeboid invasiveness in metastasis and the importance of Rho/ROCK/MLC signaling in this process. RESULTS: We analyzed the dependence of amoeboid invasiveness...

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Detalhes bibliográficos
Main Authors: Kosla, Jan, Paňková, Daniela, Plachý, Jiří, Tolde, Ondřej, Bicanová, Kristýna, Dvořák, Michal, Rösel, Daniel, Brábek, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735423/
https://ncbi.nlm.nih.gov/pubmed/23899007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-51
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