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Evidence that the RNAseH activity of the duck hepatitis B virus is unable to act on exogenous substrates

BACKGROUND: The hepadnaviral reverse transcriptase can synthesize DNA on its native RNA template within viral cores but it is usually unable to synthesize DNA employing exogenous nucleic acids as a template. The mechanism of this template commitment is unknown. Here we provide evidence that the RNAs...

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Autors principals: Gong, Yunhao, Yao, Ermei, Tavis, John E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC37354/
https://ncbi.nlm.nih.gov/pubmed/11504562
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