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Chromothripsis in a case of TP53-deficient chronic lymphocytic leukemia
We describe genomic findings in a case of CLL with del(17p13.1) by FISH, in which SNP array analysis revealed chromothripsis, a phenomenon by which regions of the cancer genome are shattered and recombined to generate frequent oscillations between two DNA copy number states. The findings illustrate...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735199/ https://ncbi.nlm.nih.gov/pubmed/23930239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2012.09.001 |
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