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Rapid loss of efficacy to the antiseizure drugs lamotrigine and carbamazepine: a novel experimental model of pharmacoresistant epilepsy

PURPOSE: Kindling is a well established model of secondarily generalized partial seizures that is widely employed in the search for novel antiseizure drugs. During the kindling and post-kindling acquisition phase, an active process of neuronal remodeling occurs. We tested the hypothesis that exposur...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Srivastava, Ajay K., Alex, Anitha B., Wilcox, Karen S., White, H. Steve
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735163/
https://ncbi.nlm.nih.gov/pubmed/23750799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12234
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