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Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine‐resistant amygdala kindling model

OBJECTIVE: The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs). This model of pharmacoresistant epilepsy has been incorp...

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Bibliografische gegevens
Gepubliceerd in:Epilepsia Open
Hoofdauteurs: Metcalf, Cameron S., Huff, Jennifer, Thomson, Kyle E., Johnson, Kristina, Edwards, Sharon F., Wilcox, Karen S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698678/
https://ncbi.nlm.nih.gov/pubmed/31440726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/epi4.12354
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