Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients

Whether elevated β-secretase (BACE) activity is related to plaque formation or amyloid β peptide (Aβ) production in Alzheimer's disease (AD) brains remains inconclusive. Here, we report that we used sandwich enzyme-linked immunoabsorbent assay to quantitate various Aβ species in the frontal cor...

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Hlavní autoři: Li, Rena, Lindholm, Kristina, Yang, Li-Bang, Yue, Xu, Citron, Martin, Yan, Riqiang, Beach, Thomas, Sue, Lucia, Sabbagh, Marwan, Cai, Huaibin, Wong, Philip, Price, Donald, Shen, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC373514/
https://ncbi.nlm.nih.gov/pubmed/14978286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0205689101
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