Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins

Four dioxin-inducible enzymes—NAD(P)H:quinone oxidoreductase-1 (NQO1) and three cytochromes P450 (CYP1A1, CYP1A2 & CYP1B1)—are implicated in both detoxication and metabolic activation of various endobiotics and xenobiotics. NQO1 is generally regarded as a cytosolic enzyme; whereas CYP1 proteins...

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Hauptverfasser: Dong, Hongbin, Shertzer, Howard G., Genter, Mary Beth, Gonzalez, Frank J., Vasiliou, Vasilis, Jefcoate, Colin, Nebert, Daniel W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735136/
https://ncbi.nlm.nih.gov/pubmed/23692925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.05.051
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