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Staying on Message: Ensuring Fidelity in Pre-mRNA Splicing

The faithful expression of genes requires that cellular machinery select substrates with high specificity at each step in gene expression. High specificity is particularly important at the stage of nuclear pre-mRNA splicing, during which the spliceosome selects splice sites and excises intervening i...

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Detalhes bibliográficos
Main Authors: Semlow, Daniel R., Jonathan P. Staley
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735133/
https://ncbi.nlm.nih.gov/pubmed/22564363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2012.04.001
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