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Regulation of Epidermal Growth Factor Receptor Signaling by Endocytosis and Intracellular Trafficking

Ligand activation of the epidermal growth factor receptor (EGFR) leads to its rapid internalization and eventual delivery to lysosomes. This process is thought to be a mechanism to attenuate signaling, but signals could potentially be generated after endocytosis. To directly evaluate EGFR signaling...

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Bibliografiske detaljer
Main Authors: Burke, Patrick, Schooler, Kevin, Wiley, H. Steven
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC37350/
https://ncbi.nlm.nih.gov/pubmed/11408594
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