Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts

Objectives are to examine the efficacy of new synthetic curcumin analogs EF31 in head and neck squamous cell carcinoma in vitro and in vivo, and study their pharmacokinetic and toxicologic effects in vivo. The synthesis of EF31 was described for the first time. Solubility of EF24, EF31 was compared...

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Bibliographic Details
Main Authors: Zhu, Shijun, Moore, Terry W., Lin, Xiaoqian, Morii, Nao, Mancini, Alessandra, Howard, Randy B., Culver, Deborah, Arrendale, Richard F., Reddy, Prabhakar, Evers, Taylor J., Zhang, Hongzheng, Sica, Gabriel, Chen, Zhuo G., Sun, Aiming, Fu, Haian, Khuri, Fadlo R., Shin, Dong M., Snyder, James P., Shoji, Mamoru
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734847/
https://ncbi.nlm.nih.gov/pubmed/22532032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ib20007d
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