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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro

The molecular events regulating the elimination of cells to create a hollow lumen during tissue development are poorly understood. By using an in vitro morphogenesis model in which MCF-10A human mammary epithelial cells form hollow acini-like structures, we have observed both caspase-mediated apopto...

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Detalhes bibliográficos
Main Authors: Mills, Kenna R., Reginato, Mauricio, Debnath, Jayanta, Queenan, Bridget, Brugge, Joan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373480/
https://ncbi.nlm.nih.gov/pubmed/14993595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400443101
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