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Imaging brain deoxyglucose uptake and metabolism by glucoCEST MRI

2-Deoxy-D-glucose (2DG) is a known surrogate molecule that is useful for inferring glucose uptake and metabolism. Although (13)C-labeled 2DG can be detected by nuclear magnetic resonance (NMR), its low sensitivity for detection prohibits imaging to be performed. Using chemical exchange saturation tr...

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Main Authors: Nasrallah, Fatima A, Pagès, Guilhem, Kuchel, Philip W, Golay, Xavier, Chuang, Kai-Hsiang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734779/
https://ncbi.nlm.nih.gov/pubmed/23673434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.79
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