The effect of the mTOR inhibitor rapamycin on glucoCEST signal in a preclinical model of glioblastoma

PURPOSE: The mammalian target of rapamycine (mTOR) is an enzyme that regulates cell metabolism and proliferation. It is up-regulated in aggressive tumors such as glioblastoma, leading to increased glucose uptake and consumption. It has been suggested that glucose Chemical Exchange Saturation Transfe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Magn Reson Med
Egile Nagusiak: Xu, Xiang, Xu, Jiadi, Knutsson, Linda, Liu, Jing, Liu, Huanling, Li, Yuguo, Lal, Bachchu, Laterra, John, Artemov, Dmitri, Liu, Guanshu, van Zijl, Peter C. M., Chan, Kannie W. Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482943/
https://ncbi.nlm.nih.gov/pubmed/30793789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.27683
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