Prostaglandin E(2) type 1 receptors contribute to neuronal apoptosis after transient forebrain ischemia

Cyclooxygenase-2-derived prostaglandin E(2) (PGE(2)) contributes to excitotoxic and ischemic neuronal cell death by engaging neuronal PGE(2) type 1 receptors (EP1R). Our previous studies have shown that EP1R signaling resulted in disturbances of intracellular Ca(2+) homeostasis and suppression of th...

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Detalhes bibliográficos
Main Authors: Shimamura, Munehisa, Zhou, Ping, Casolla, Barbara, Qian, Liping, Capone, Carmen, Kurinami, Hitomi, Iadecola, Costantino, Anrather, Josef
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734771/
https://ncbi.nlm.nih.gov/pubmed/23632967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.69
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