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Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR

G protein-coupled receptors are cell-surface seven-helical membrane proteins that undergo conformational changes on activation. The mammalian photoreceptor, rhodopsin, is the best-studied member of this superfamily. Here, we provide the first evidence that activation in rhodopsin may involve differe...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Klein-Seetharaman, Judith, Yanamala, Naveena V. K., Javeed, Fathima, Reeves, Philip J., Getmanova, Elena V., Loewen, Michele C., Schwalbe, Harald, Khorana, H. Gobind
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373475/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14990789/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308713101
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