Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR

G protein-coupled receptors are cell-surface seven-helical membrane proteins that undergo conformational changes on activation. The mammalian photoreceptor, rhodopsin, is the best-studied member of this superfamily. Here, we provide the first evidence that activation in rhodopsin may involve differe...

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Autores principales: Klein-Seetharaman, Judith, Yanamala, Naveena V. K., Javeed, Fathima, Reeves, Philip J., Getmanova, Elena V., Loewen, Michele C., Schwalbe, Harald, Khorana, H. Gobind
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC373475/
https://ncbi.nlm.nih.gov/pubmed/14990789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308713101
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