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MyoD Gene Suppression by Oct4 Is Required for Reprogramming in Myoblasts to Produce Induced Pluripotent Stem Cells

Expression of the four transcription factors, that is, Oct4, Sox2, cMyc, and Klf4 has been shown to generate induced pluripotent stem cells (iPSCs) from many types of specialized differentiated somatic cells. It remains unclear, however, whether fully committed skeletal muscle progenitor cells (myob...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Watanabe, Shuichi, Hirai, Hiroyuki, Asakura, Yoko, Tastad, Christopher, Verma, Mayank, Keller, Charles, Dutton, James R., Asakura, Atsushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734538/
https://ncbi.nlm.nih.gov/pubmed/21425413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.598
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