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MyoD Gene Suppression by Oct4 Is Required for Reprogramming in Myoblasts to Produce Induced Pluripotent Stem Cells

Expression of the four transcription factors, that is, Oct4, Sox2, cMyc, and Klf4 has been shown to generate induced pluripotent stem cells (iPSCs) from many types of specialized differentiated somatic cells. It remains unclear, however, whether fully committed skeletal muscle progenitor cells (myob...

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Detalhes bibliográficos
Main Authors: Watanabe, Shuichi, Hirai, Hiroyuki, Asakura, Yoko, Tastad, Christopher, Verma, Mayank, Keller, Charles, Dutton, James R., Asakura, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734538/
https://ncbi.nlm.nih.gov/pubmed/21425413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.598
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