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Triptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblasts

BACKGROUND: Extracts of Tripterygium wilfordii Hook F (TWHF), a traditional Chinese herb, have been reported to show efficacy in patients with rheumatoid arthritis (RA). Since RA is not only characterized by inflammation but also by synovial proliferation in the joints, we examined whether triptolid...

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Detalhes bibliográficos
Main Authors: Kusunoki, Natsuko, Yamazaki, Ryuta, Kitasato, Hidero, Beppu, Moroe, Aoki, Haruhito, Kawai, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373449/
https://ncbi.nlm.nih.gov/pubmed/15040811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-4-2
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