Strong positional preference in the interaction of LNA oligonucleotides with DNA polymerase and proofreading exonuclease activities: implications for genotyping assays

The effect of locked nucleic acid (LNA) modification position upon representative DNA polymerase and exonuclease activities has been examined for potential use in primer extension genotyping applications. For the 3′→5′ exonuclease activities of four proofreading DNA polymerases (Vent, Pfu, Klenow fr...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Di Giusto, Daniel A., King, Garry C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2004
Assuntos:	NAR Methods Online
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14973328/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh036
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