A mutation in polynucleotide phosphorylase from Escherichia coli impairing RNA binding and degradosome stability

Polynucleotide phosphorylase (PNPase), a 3′ to 5′ exonuclease encoded by pnp, plays a key role in Escherichia coli RNA decay. The enzyme, made of three identical 711 amino acid subunits, may also be assembled in the RNA degradosome, a heteromultimeric complex involved in RNA degradation. PNPase auto...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Regonesi, Maria Elena, Briani, Federica, Ghetta, Andrea, Zangrossi, Sandro, Ghisotti, Daniela, Tortora, Paolo, Dehò, Gianni
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
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Articles
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373403/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14963263/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh268
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