Contingency nature of Helicobacter bizzozeronii oxygen-insensitive NAD(P)H-nitroreductase (HBZC1_00960) and its role in metronidazole resistance

Genomic analysis of a metronidazole resistant H. bizzozeronii strain revealed a frame length extension of the oxygen-insensitive NAD(P)H-nitroreductase HBZC1_00960 (RdxA), associated with the disruption of the C-terminal cysteine-containing conserved region (IACLXALGK). This was the result of the ex...

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Autores principales: Kondadi, Pradeep Kumar, Pacini, Claudia, Revez, Joana, Hänninen, Marja-Liisa, Rossi, Mirko
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734016/
https://ncbi.nlm.nih.gov/pubmed/23865636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-44-56
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