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3-Aryl-3-arylmethoxyazetidines. A new class of high affinity ligands for monoamine transporters
A series of 3-aryl-3-arylmethoxy-azetidines were synthesized and evaluated for binding affinities at dopamine and serotonin transporters. The 3-aryl-3–arylmethoxyazetidines were generally SERT selective with the dichloro substituted congener 7c (K(i) = 1.0 nM) and the tetrachloro substituted derivat...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733996/ https://ncbi.nlm.nih.gov/pubmed/23806554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.05.071 |
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