Proteomic Analysis of Signaling Network Regulation in Renal Cell Carcinomas with Differential Hypoxia-Inducible Factor-2α Expression

BACKGROUND: The loss of von Hippel–Lindau (VHL) protein function leads to highly vascular renal tumors characterized by an aggressive course of disease and refractoriness to chemotherapy and radiotherapy. Loss of VHL in renal tumors also differs from tumors of other organs in that the oncogenic casc...

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Main Authors: Nagaprashantha, Lokesh Dalasanur, Talamantes, Tatjana, Singhal, Jyotsana, Guo, Jia, Vatsyayan, Rit, Rauniyar, Navin, Awasthi, Sanjay, Singhal, Sharad S., Prokai, Laszlo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733962/
https://ncbi.nlm.nih.gov/pubmed/23940778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071654
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