TNF-α Acts as an Immunoregulator in the Mouse Brain by Reducing the Incidence of Severe Disease Following Japanese Encephalitis Virus Infection

Japanese encephalitis virus (JEV) causes acute central nervous system (CNS) disease in humans, in whom the clinical symptoms vary from febrile illness to meningitis and encephalitis. However, the mechanism of severe encephalitis has not been fully elucidated. In this study, using a mouse model, we i...

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Detalhes bibliográficos
Main Authors: Hayasaka, Daisuke, Shirai, Kenji, Aoki, Kotaro, Nagata, Noriyo, Simantini, Dash Sima, Kitaura, Kazutaka, Takamatsu, Yuki, Gould, Ernest, Suzuki, Ryuji, Morita, Kouichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733918/
https://ncbi.nlm.nih.gov/pubmed/23940775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071643
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