TNF-α Acts as an Immunoregulator in the Mouse Brain by Reducing the Incidence of Severe Disease Following Japanese Encephalitis Virus Infection

Japanese encephalitis virus (JEV) causes acute central nervous system (CNS) disease in humans, in whom the clinical symptoms vary from febrile illness to meningitis and encephalitis. However, the mechanism of severe encephalitis has not been fully elucidated. In this study, using a mouse model, we i...

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Bibliographic Details
Main Authors: Hayasaka, Daisuke, Shirai, Kenji, Aoki, Kotaro, Nagata, Noriyo, Simantini, Dash Sima, Kitaura, Kazutaka, Takamatsu, Yuki, Gould, Ernest, Suzuki, Ryuji, Morita, Kouichi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733918/
https://ncbi.nlm.nih.gov/pubmed/23940775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071643
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