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A new γ-interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetase

Two forms of human tryptophanyl-tRNA synthetase (TrpRS) are produced in vivo through alternative mRNA splicing. The two forms, full-length TrpRS and mini TrpRS, are catalytically active, but are distinguished by the striking anti-proliferative and anti-angiogenic activity specific to mini TrpRS. Her...

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Detalhes bibliográficos
Main Authors: Liu, Jianming, Shue, Eveline, Ewalt, Karla L., Schimmel, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373357/
https://ncbi.nlm.nih.gov/pubmed/14757836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh240
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