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A new γ-interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetase
Two forms of human tryptophanyl-tRNA synthetase (TrpRS) are produced in vivo through alternative mRNA splicing. The two forms, full-length TrpRS and mini TrpRS, are catalytically active, but are distinguished by the striking anti-proliferative and anti-angiogenic activity specific to mini TrpRS. Her...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373357/ https://ncbi.nlm.nih.gov/pubmed/14757836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh240 |
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