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In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs
Over-expression of ABCG2 is linked to multidrug resistance in cancer chemotherapy. We have previously shown that functionalized aurones effectively reduced the efflux of pheophorbide A (an ABCG2 substrate) from ABCG2 over-expressing MDA-MB-231/R (“R”) cells. In the present report, we investigated th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733550/ https://ncbi.nlm.nih.gov/pubmed/21855533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.08.002 |
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