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TALE-mediated modulation of transcriptional enhancers
We tested whether Transcription Activator-Like Effectors (TALEs) can mediate repression and activation of endogenous enhancers in the Drosophila genome. TALE-repressors (TALERs) targeting each of the five even-skipped (eve) “stripe” enhancers generated repression specifically of the focal stripes. T...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733453/ https://ncbi.nlm.nih.gov/pubmed/23817068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2543 |
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