Wird geladen...

Ab initio calculations and validation of the pH-dependent structures of the His37-Trp41 quartet, the heart of acid activation and proton conductance in the M2 protein of Influenza A virus

The M2 protein of Influenza A virus forms a homotetrameric proton channel activated by low pH. The His37-Trp41 quartet is the heart of acid activation and proton conductance, but the functional mechanism is still controversial. We carried out ab initio calculations to model the pH-dependent structur...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Dong, Hao, Yi, Myunggi, Cross, Timothy A., Zhou, Huan-Xiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733280/
https://ncbi.nlm.nih.gov/pubmed/23930201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC50293G
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!