Llwytho...

Ab initio calculations and validation of the pH-dependent structures of the His37-Trp41 quartet, the heart of acid activation and proton conductance in the M2 protein of Influenza A virus

The M2 protein of Influenza A virus forms a homotetrameric proton channel activated by low pH. The His37-Trp41 quartet is the heart of acid activation and proton conductance, but the functional mechanism is still controversial. We carried out ab initio calculations to model the pH-dependent structur...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dong, Hao, Yi, Myunggi, Cross, Timothy A., Zhou, Huan-Xiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733280/
https://ncbi.nlm.nih.gov/pubmed/23930201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC50293G
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