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Two mutations in the tetracycline repressor change the inducer anhydrotetracycline to a corepressor

We report for the first time the in vitro characterization of a reverse tetracycline repressor (revTetR). The dimeric wild-type repressor (TetR) binds to tet operator tetO in the absence of the inducer anhydrotetracycline (atc) to confer tight repression. We have isolated the revTetR G96E L205S muta...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kamionka, Annette, Bogdanska-Urbaniak, Joanna, Scholz, Oliver, Hillen, Wolfgang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC373327/
https://ncbi.nlm.nih.gov/pubmed/14764926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh200
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