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Mimicking the BH3 domain to kill cancer cells

Cancer cells demonstrate deviant behavior that induces apoptotic signaling. In order to survive, cancer cells typically acquire changes enabling evasion of death signals. One way they do this is by increasing the expression of anti-apoptotic BCL-2 proteins. Anti-apoptotic BCL-2 family proteins antag...

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Bibliografske podrobnosti
Main Authors: Chonghaile, Triona Ni, Letai, Anthony
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733265/
https://ncbi.nlm.nih.gov/pubmed/19641500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.52
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