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Recurrent Rearrangements in Prostate Cancer: Causes and Therapeutic Potential

DNA damage and genetic rearrangements are hallmarks of cancer. However, gene fusions as driver mutations in cancer have classically been a distinction in leukemia and other rare instances until recently with the discovery of gene fusion events occurring in 50 to 75% of prostate cancer patients. The...

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Autori principali: White, Nicole M., Feng, Felix Y, Maher, Christopher A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733264/
https://ncbi.nlm.nih.gov/pubmed/23410129
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