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The Kisspeptin Signaling Pathway and its Role in Human Isolated GnRH Deficiency

Amplification of the neurosecretory activity of the GnRH system is the defining neuroendocrine even for sexual maturation. The physiological mechanisms that drive GnRH secretion at puberty have been difficult to identify but the discovery in 2003 that the G protein coupled receptor KISS1R is a key r...

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Bibliografiske detaljer
Main Authors: Wahab, Fazal, Quinton, Richard, Seminara, Stephanie B.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733256/
https://ncbi.nlm.nih.gov/pubmed/21704672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.05.043
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