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The Kisspeptin Signaling Pathway and its Role in Human Isolated GnRH Deficiency

Amplification of the neurosecretory activity of the GnRH system is the defining neuroendocrine even for sexual maturation. The physiological mechanisms that drive GnRH secretion at puberty have been difficult to identify but the discovery in 2003 that the G protein coupled receptor KISS1R is a key r...

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Detalhes bibliográficos
Main Authors: Wahab, Fazal, Quinton, Richard, Seminara, Stephanie B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733256/
https://ncbi.nlm.nih.gov/pubmed/21704672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.05.043
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