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TGFβ-mediated signaling and transcriptional regulation in pancreatic development and cancer

Transforming growth factor-β (TGFβ) plays a critical role in pancreatic development and cell proliferation. Binding of TGFβ to its membrane receptor kinases activates the Smad signaling proteins, allowing them to translocate to the nucleus and participate in the transcriptional control of TGFβ targe...

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Autors principals: Ellenrieder, Volker, Fernandez Zapico, Martin E., Urrutia, Raul
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733232/
https://ncbi.nlm.nih.gov/pubmed/17031197
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