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TGFβ-mediated signaling and transcriptional regulation in pancreatic development and cancer
Transforming growth factor-β (TGFβ) plays a critical role in pancreatic development and cell proliferation. Binding of TGFβ to its membrane receptor kinases activates the Smad signaling proteins, allowing them to translocate to the nucleus and participate in the transcriptional control of TGFβ targe...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733232/ https://ncbi.nlm.nih.gov/pubmed/17031197 |
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