A Novel PGC-1α Isoform in Brain Localizes to Mitochondria and Associates with PINK1 and VDAC

Peroxisome proliferator-activated receptor-gamma co-activator 1α (PGC-1α) and PTEN-induced putative kinase 1 (PINK1) are powerful regulators of mitochondrial function. Here, we report that a previously unrecognized, novel 35 kDa PGC-1α isoform localizes to the mitochondrial inner membrane and matrix...

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Autores principales: Choi, Joungil, Batchu, Vera Venkatanaresh Kumar, Schubert, Manfred, Castellani, Rudolph J., Russell, James W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733220/
https://ncbi.nlm.nih.gov/pubmed/23688429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.05.041
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